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GeneNote, GeneAnnot, GeneLoc, GeneTide, GeneALaCart and GeneDecks are a suite of specialized databases and applications that are integrated with GeneCards®
These databases concentrate on batch-querying applications, associations between various sets of genes and their products, gene expression in gene expression in human tissues, gene microarray annotation, gene location and organization and analysis of Expressed Sequence Tags (ESTs). The suite of GeneCards® related databases helps researchers overcome the bottleneck of data analysis in biology and offers a profound understanding of the role of individual genes and of the way genes function together.
GeneALaCart
GeneALaCart is a batch-querying application based on the popular GeneCards® database. It allows retrieval of information about multiple genes in a batch query.
GeneDecks
GeneDecks provides sets of associated genes through similarity of GeneCards annotation to a selected gene. GeneDecks is accessed through the various sections of a gene card.
GeneNote
GeneNote is a database of human genes and their expression profiles in healthy tissues.
It is based on Weizmann Institute of Science DNA array experiments, which were performed on the Affymetrix HG-U95 set A-E.
It offers:
For more information, see http://genecards.weizmann.ac.il/GeneNote/.
For publication, see:
http://genecards.weizmann.ac.il/cgi-bin/genenote/publications_page.pl
and
http://bioinformatics.weizmann.ac.il/cards/publications.shtml.
GeneAnnot
GeneAnnot provides data on annotation of probe sets by direct sequence comparisons of probes to mRNA sequences.
Annotation of probe sets is revised and improved by direct sequence comparison of probes to
GenBank, RefSeq and Ensembl mRNA sequences.
Whenever possible, probe sets are related to GeneCards® genes,
while assigning sensitivity and specificity scores to each probe-set to gene match. In the remaining cases,
probe sets are annotated by their relation to GenBank mRNA sequences and
UniGene clusters. The results are integrated with
GeneCards®, GeneLoc and GeneNote databases.
For more information, see http://genecards.weizmann.ac.il/geneannot/.
For publication, see: http://genecards.weizmann.ac.il/cgi-bin/genenote/publications_page.pl
and http://bioinformatics.weizmann.ac.il/cards/publications.shtml.
GeneLoc
The GeneLoc algorithm creates an integrated map of the human genome. GeneLoc unifies gene collections, eliminates
redundancies, and assigns each gene a meaningful location-based identifier, which also serves as its GeneCards ID.
GeneLoc currently uses gene sets from NCBI and Ensembl. It compares these collections, deciding which entries should be
consolidated and which are discrete. Since the gene annotations use the same assembly and coordinate scheme, GeneLoc
effects this gene integration by comparing genomic locations. The resulting GeneLoc 'gene territory' reflects the range
of the unified genes, taking into account every exon.
Additionally, DNA segments, classified by categories (such as STSs mapped by various methods and EST clusters) are
presented, alongside the genes, on a Megabase-scale map, with further information and links to relevant databases.
For more information, see http://genecards.weizmann.ac.il/geneloc/.
For publication, see: http://bioinformatics.weizmann.ac.il/cards/publications.shtml.
GeneTide
GeneTide is an automated system for human transcripts (mRNA & ESTs) annotation and elucidation of de-novo genes
GeneTide integrates various data resources in order to create a comprehensive list of human genes.
This is done by association between the set of over ~5.5 million human ESTs currently available from dbEST and mRNA
sequences from GenBank to the set of ~35,000 human genes as defined in GeneCards.
Using GeneTide, transcripts (mRNA & EST) can be:
For more information, see http://genecards.weizmann.ac.il/genetide/.
For publication, see: http://bioinformatics.weizmann.ac.il/cards/publications.shtml.
